Thanks to the unceasing development of pharmaceutical industry, the world has recently gained a new medication that was created to help people solve weight-management problems. Obese and overweight people often find it difficult to lose weight and they have to recourse to special medications. After the manufacturers have conducted several clinical trials, in 2014 Contrave weight loss pill became available on the market.
Contrave contains two main ingredients – Bupropion and Naltrexone; in a combination these two drugs reduce food carvings, so the patient needs a smaller quantity of food to get the feeling of satiety. This effect alone, however, is not enough to achieve a satisfactory result, which is why the doctors recommend that the patients take Contrave as prescribed and at the same time increase daily physical activity and follow a low-calorie diet.
Bupropion and Naltrexone when taken apart are not prescribed for weight-management purposes. Bupropion is a drug used to treat various depressive disorders, but Naltrexone is prescribed to help patients get rid of addictions. The patients who are prescribed Contrave should be aware that Bupropion and Naltrexone produce changes in the central nervous system, so during the treatment period the patient should regularly visit their physician and inform the doctor if they start experiencing any unpleasant side effects.
One must keep in mind that although Contrave ingredients separately have antidepressant and anti-addiction effects, the weight loss drug should not be used to treat these medical conditions; it is to be used for weight loss only. Unlike many other weight loss drugs, Contrave does not lead to fat burning, but the trials have shown that due to its influence on the nervous system, it suppresses food carvings, which is the first and probably the most important step in the weight loss process. Apart from this Contrave weight loss drug is known to speed up metabolism and increase internal temperature of the body, which is also important for the process of weight loss. The efficiency of Contrave was analyzed by the U.S. Food and Drug Administration based on the results of several clinical trials. After the assessment the drug was approved by the FDA and since 2014 it is available with a prescription.
Although Contrave is a powerful medication, the patients should know that the final result depends on them as much as on the drug they are taking. If one continues to eat in excess and doesn’t exercise on a regular basis, the drug might not help them lose weight. The key to success is a complex approach which involves a lot of effort from the patient’s side.
The trials that were carried out prior to the approval of Contrave demonstrated the efficiency of the drug, however some other tests and studies are necessary as it is extremely important to analyze all the possible effects, both positive and negative, that the drug can bring about.
Many Contrave reviews only focus upon the positive effects of the medication, but it is also important to know how exactly the trials were carried out and what negative effects they revealed.
The trials involved people with the Body Mass Index of 27 and above (overweight) who also have certain health problems brought about by the excessive weight and people with BMI of 30 or more (overweight) with or without such conditions. The studies have demonstrated that Contrave indeed helps people lose weight if it is correctly administered. The patients who were treated with Contrave, followed a healthy diet and took regular physical exercise lost from 3 to 7% of their weight (5% on the average), while the results of the placebo group were far from satisfactory.
However inspiring this data might be, a number of patients had to stop the treatment because of the side effects brought about by the medication. A big number of patients experienced nausea almost permanently and many of them interrupted the treatment just to get rid of this adverse reaction.
The second trial of Contrave involved a higher number of patients suffering from excessive weight – 1742 people of different sex and age. The results of this trial were also encouraging as the majority of people lost at least 5% of their weight or more during the trial period.
Accurate Contrave reviews contain detailed information about all the side effects caused by Contrave. One can see that the number of adverse reactions that the patients might experience is a bit higher than it could have been expected. Nausea is the most common of them, but also the least serious.
The most severe undesired changes occur on the psychological level. The patients are known to experience depression, anxiety, even suicidal thoughts. Headaches and insomnia are also frequent. The patient’s behavior can change while they are taking Contrave – they can become aggressive and experience mood swings.
On the physiological level Contrave can be the cause of such adverse reactions as vomiting, constipation, diarrhea and dizziness.
Make sure you read carefully the medication instruction and find out as much information as possible on Contrave before you start taking it. Address a specialist if you think that you need some medication help to lose weight and follow the doctor’s guidance on how to take the medicine. Do not increase or reduce the recommended dose. Before prescribing Contrave the doctor must be informed about all the medical conditions you have or had and about all the medications you are taking now or took during the last 14 days.
Do not take Contrave if you are pregnant or are currently breastfeeding as the medication might damage the baby’s health.
Strictly follow all the doctor’s recommendations and in case you experience any unpleasant adverse reactions, contact your physician immediately.